Kev siv crospovidone yog dab tsi?
Crospovidone yog ib qho dej-insoluble ntsiav tshuaj disintegrant. Nws yog siv nyob rau hauv ncaj qha compression thiab qhuav los yog ntub granulation thiab tableting txheej txheem ntawm ib tug concentration ntawm 2-5%; Crospovidone tuaj yeem ua rau pom kev ua haujlwm siab capillary sai thiab muaj peev xwm hydration zoo heev, yuav luag tsis muaj gel; Cov kev tshawb fawb pom tau hais tias qhov loj ntawm crospovidone hais muaj zog cuam tshuam rau kev puas tsuaj ntawm cov tshuaj tua kab mob thiab tshuaj tua kab mob, thiab crospovidone nrog cov khoom loj tuaj yeem ua tau zoo dua li cov khoom me me. Ceev disintegration nyhuv. Hla-txuas povidone yog ib qho zoo heev disintegrant. Thaum 1-2% yog siv rau hauv cov ntsiav tshuaj, qhov kev sib cais ntawm lwm cov khoom siv feem ntau siv tau tuaj yeem tau txais, thiab nws muaj kev ua haujlwm zoo, uas yog, thaum rov ua dua thiab ua haujlwm. , Tsis tas yuav ntxiv ntau cov disintegrant, nws yog hu ua super disintegrant.
Tom qab crospovidone yog siv los ua ib qho disintegrant thiab compressed rau hauv cov ntsiav tshuaj, cov ntsiav tshuaj muaj siab hardness, luv luv disintegration lub sij hawm txwv, thiab siab dissolution tus nqi; nws muaj zog ruaj khov thiab yuav tsis hloov raws sijhawm.
Hla-txuas povidone kuj tuaj yeem siv los ua cov ntaub qhwv qhuav, muab tub lim, thiab cov khoom ntxiv rau cov ntsiav tshuaj, tshuaj ntsiav, thiab granules. Qhov me me me tuaj yeem txo cov cim ntawm sab ntawm cov ntsiav tshuaj compressed thiab txhim kho cov ntsiav tshuaj ua haujlwm. Tsis sib xws, tus nqi ib txwm yog 20-80mg / ntsiav tshuaj.
Hla-txuas povidone kuj tseem tuaj yeem siv los ua cov tshuaj tua kab mob. Co-evaporation thev naus laus zis tuaj yeem ua kom cov kua dej tsis zoo ntawm cov tshuaj tsis zoo: ua ntej, cov tshuaj yog adsorbed ntawm cross-linked povidone nrog cov kuab tshuaj tsim nyog, thiab tom qab ntawd cov kuab tshuaj yog evaporated. Cov tshuab no tuaj yeem tau txais tus nqi tawg sai dua.
Cov khoom no kuj tau siv dav hauv kev lim dej hauv kev tsim cov cawv txiv hmab thiab vinegar hauv kev lag luam khoom noj kom tshem tawm cov enzymes thiab cov protein.
Hla-txuas povidone thiab polyphenols tuaj yeem tsim cov complexes ruaj khov, uas tuaj yeem siv los kho cov dej-soluble los yog cawv-muaj tshuaj ntsuab rho tawm thiab tinctures los txhim kho kev ruaj ntseg ntawm cov nroj tsuag tshuaj.